Hyperbaric oxygen and bone marrow-derived endothelial progenitor cells in diabetic wound healing. | Canada Hyperbarics Skip to main content
Review Vascular 2006

Hyperbaric oxygen and bone marrow-derived endothelial progenitor cells in diabetic wound healing.

Gallagher KA, Goldstein LJ, Thom SR, Velazquez OC — Vascular, 2006

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reviewed existing literature on how hyperbaric oxygen therapy affects endothelial progenitor cells and their role in diabetic wound healing.

What They Found

They found that endothelial progenitor cells (EPCs) are crucial for wound healing, but their number and function are significantly impaired in diabetic patients. Evidence suggests that hyperbaric oxygen therapy (HBO2) can increase the mobilization of EPCs from bone marrow into the bloodstream, potentially improving healing in chronic wounds associated with diabetes and peripheral arterial disease.

Canadian Relevance

This review article does not have a direct Canadian connection.

Study Limitations

As a review article, this study synthesizes existing literature and postulates future research directions rather than presenting new experimental data or clinical trial results.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Review
Category Wound Care
Source Pubmed
PubMed ID 17150153
Year Published 2006
Journal Vascular
MeSH Terms Animals; Bone Marrow Cells; Cell Movement; Diabetes Mellitus; Diabetic Foot; Endothelial Cells; Humans; Hyperbaric Oxygenation; Mice; Neovascularization, Physiologic; Nitric Oxide; Nitric Oxide Synthase; Peripheral Vascular Diseases; Treatment Outcome; Wound Healing

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology