Hyperbaric oxygen and radiotherapy: a Medical Research Council trial in carcinoma of the bladder | Canada Hyperbarics Skip to main content
RCT Br J Radiol 1978

Hyperbaric oxygen and radiotherapy: a Medical Research Council trial in carcinoma of the bladder

Cade I, McEwen J, Dische S, Saunders M, Watson E, Halnan K, et al. — Br J Radiol, 1978

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

Researchers conducted a randomized controlled trial in the United Kingdom involving 241 bladder cancer patients to determine if adding hyperbaric oxygen to standard radiation therapy improved outcomes.

What They Found

This study, involving 241 bladder cancer patients across four UK centres, found no additional benefit when hyperbaric oxygen was used alongside radiation therapy. Patients receiving hyperbaric oxygen did not show better outcomes compared to those receiving radiation therapy with air.

What This Means for Canadian Patients

This 1978 study suggests that hyperbaric oxygen therapy may not improve outcomes for Canadian patients undergoing radiation treatment for bladder cancer. Patients should discuss all treatment options with their healthcare team, as current cancer treatments and HBOT protocols have evolved significantly since this research.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

A limitation of this 1978 study is that medical treatments and hyperbaric oxygen protocols have advanced considerably in the decades since its publication.

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Study Details

Study Type RCT
Category Uncategorised
Source Pubmed
PubMed ID 361143
Year Published 1978
Journal Br J Radiol
MeSH Terms Air; Clinical Trials as Topic; Humans; Hyperbaric Oxygenation; Radiotherapy Dosage; Random Allocation; Urinary Bladder Neoplasms

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.