Hyperbaric oxygen for patients with chronic bowel dysfunction after pelvic radiotherapy (HOT2): a randomised, double-blind, sham-controlled phase 3 trial. | Canada Hyperbarics Skip to main content
RCT The Lancet. Oncology 2016

Hyperbaric oxygen for patients with chronic bowel dysfunction after pelvic radiotherapy (HOT2): a randomised, double-blind, sham-controlled phase 3 trial.

Glover M, Smerdon GR, Andreyev HJ, Benton BE, Bothma P, Firth O, et al. — The Lancet. Oncology, 2016

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a double-blind, sham-controlled, phase 3 randomized trial to assess hyperbaric oxygen therapy versus sham treatment for 8 weeks in patients with chronic bowel dysfunction after pelvic radiotherapy.

What They Found

The provided abstract does not contain the results of the study, so specific findings and numbers regarding the efficacy of hyperbaric oxygen therapy cannot be reported. The trial aimed to provide conclusive results for the clinical benefits of hyperbaric oxygen in patients with chronic bowel dysfunction after radiotherapy for pelvic malignancies.

What This Means for Canadian Patients

If hyperbaric oxygen therapy were found to be effective, it could offer a new treatment option for Canadian patients experiencing chronic bowel dysfunction after pelvic radiotherapy. However, without the study's findings, its practical implications for patient care in Canada remain unknown.

Canadian Relevance

This study was not conducted in Canada and does not have a direct Canadian connection.

Study Limitations

The generalizability of these findings to diverse patient populations and the long-term efficacy of the treatment would require further investigation.

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Study Details

Study Type RCT
Category Radiation Injury
Source Pubmed
PubMed ID 26703894
Year Published 2016
Journal The Lancet. Oncology
MeSH Terms Adult; Aged; Aged, 80 and over; Chronic Disease; Double-Blind Method; Female; Gastrointestinal Diseases; Gastrointestinal Hemorrhage; Humans; Hyperbaric Oxygenation; Male; Middle Aged; Pelvic Neoplasms; Radiation Injuries; Radiotherapy

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.