What Researchers Did
Researchers conducted a trial to evaluate hyperbaric oxygen therapy in 10 patients with perianal Crohn's disease that had not responded to conventional treatments.
What They Found
Complete healing was observed in 5 out of 10 patients after one to two courses of hyperbaric oxygen therapy, with an additional 2 patients achieving complete healing after three courses. Overall, 70% of patients experienced complete healing, and 1 patient improved while 2 did not improve, with no adverse effects reported and no recurrence over an 18-month follow-up.
Canadian Relevance
This study has no direct Canadian connection as it was not conducted in Canada or by Canadian researchers.
Study Limitations
A significant limitation of this study is its small sample size of only 10 patients, which means the findings are preliminary and require further validation in larger trials.