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RCT PLoS ONE 2013

Hyperbaric oxygen induces late neuroplasticity in post stroke patients

Efrati S, Fishlev G, Bechor Y, et al. — PLoS ONE, 2013

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

Researchers conducted a randomized controlled trial with 59 chronic stroke patients to evaluate if hyperbaric oxygen therapy (HBOT) could improve neurological functions and brain activity.

What They Found

Patients in both the treated and cross groups showed significant improvements in neurological functions and quality of life after 40 hyperbaric oxygen therapy sessions. No improvements were observed during the 2-month control period, and SPECT imaging confirmed elevated brain activity correlated with clinical improvements.

Canadian Relevance

This study was not conducted in Canada and does not have a direct Canadian connection.

Study Limitations

A limitation of this study is its relatively small sample size of 59 patients, which may affect the generalizability of the findings.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type RCT
Category Neurological
Source Pubmed
PubMed ID 23335971
Year Published 2013
Journal PLoS ONE

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: March 19, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology