What Researchers Did
Researchers investigated the effects of hyperbaric oxygen treatment (HBO) on contused calf muscles in a rat skeletal muscle injury model, treating rats with 100% oxygen daily.
What They Found
HBO reduced early lower limb swelling and muscle wet weight, and significantly improved muscle isometric strength 7 days post-injury. It initially suppressed circulating macrophages but later accelerated their invasion into injured muscle, also increasing proliferating satellite cells and regenerated muscle fibers.
Canadian Relevance
This study has no direct Canadian connection as it was not conducted in Canada, nor did it involve Canadian researchers or patients.
Study Limitations
The primary limitation is that this study was conducted in a rat model, meaning its findings may not directly translate to human patients.