Study Actas Urol Esp 2011

Hyperbaric oxygen therapy adjunctive to surgical debridement in management of Fournier's gangrene: usefulness of a severity index score in predicting disease gravity and patient survival

Janane A, Hajji F, Ismail T, Chafiqui J, Ghadouane M, Ameur A, et al. — Actas Urol Esp, 2011

View Original on PubMed PMID 21496959

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers studied 70 patients with Fournier's gangrene to evaluate the effectiveness of surgical debridement combined with hyperbaric oxygen therapy (HBOT) and the usefulness of a severity index score.

What They Found

Out of 70 patients with Fournier's gangrene treated with surgery and HBOT, 8 (11.4%) died, while 62 (88.5%) survived. The median body surface area affected by the infection was significantly smaller in survivors (2.4%) compared to non-survivors (4.9%). The Fournier's Gangrene Severity Index (FGSI) score did not accurately predict the disease's severity or patient survival.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

This study was retrospective and did not include a control group of patients who received only surgical debridement, which limits direct comparison of treatment effectiveness.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type	Study
Category	Infection
Source	Pubmed
PubMed ID	21496959
Year Published	2011
Journal	Actas Urol Esp
MeSH Terms	Adult; Aged; Anti-Bacterial Agents; Cephalosporins; Combined Modality Therapy; Debridement; Fournier Gangrene; Humans; Hyperbaric Oxygenation; Male; Metronidazole; Middle Aged; Prognosis; Retrospective Studies; Severity of Illness Index; Survival Analysis; Treatment Outcome

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 17, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology