Hyperbaric oxygen therapy. Clinical use in treatment of osteomyelitis, osteoradionecrosis and reconstructive surgery of the irradiated mandible. | Canada Hyperbarics Skip to main content
Clinical Study Mund-, Kiefer- und Gesichtschirurgie : MKG 2000

Hyperbaric oxygen therapy. Clinical use in treatment of osteomyelitis, osteoradionecrosis and reconstructive surgery of the irradiated mandible.

Jamil MU, Eckardt A, Franko W — Mund-, Kiefer- und Gesichtschirurgie : MKG, 2000

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers treated 28 patients with hyperbaric oxygen therapy for various oral and maxillofacial conditions, including osteomyelitis, osteoradionecrosis, and threatened transplants.

What They Found

Among 28 patients, 6 of 16 with chronic osteomyelitis healed completely, and 8 others showed clinical improvement. Both patients with osteoradionecrosis improved, all 9 patients with threatened grafts showed good healing, and the single patient with a non-healing wound was cured.

What This Means for Canadian Patients

Hyperbaric oxygen therapy could offer a valuable treatment option for Canadian patients suffering from severe oral and maxillofacial conditions like treatment-resistant osteomyelitis, osteoradionecrosis, and compromised surgical grafts. This therapy may help improve healing outcomes and potentially prevent further complications in cases where conventional treatments are insufficient.

Canadian Relevance

This study has no direct Canadian connection as it was conducted at a medical school in Hannover, Germany.

Study Limitations

The study's main limitations include its small sample size and single-center design, and the absence of a control group for comparison.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Clinical Study
Category Radiation Injury
Source Pubmed
PubMed ID 11092186
Year Published 2000
Journal Mund-, Kiefer- und Gesichtschirurgie : MKG
MeSH Terms Adult; Aged; Bone Transplantation; Female; Follow-Up Studies; Humans; Hyperbaric Oxygenation; Male; Mandible; Mandibular Diseases; Mandibular Neoplasms; Middle Aged; Osteomyelitis; Osteoradionecrosis; Treatment Outcome

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This study relates to Delayed Radiation Injury. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology