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Pilot Study Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc 2015

Hyperbaric oxygen therapy for choroidal neovascularization: a pilot study.

Malerbi FK, Novais EA, Emmerson Badaró, Bonomo PP, Pereira AJ, Lottenberg CL, et al. — Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc, 2015

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a pilot study where seven patients with active choroidal neovascularization (CNV) received 10 daily hyperbaric oxygen therapy sessions, with some subsequently receiving anti-VEGF treatment.

What They Found

At the end of follow-up (average 150 days), five out of seven patients (71%) showed anatomical improvement in CNV, one maintained, and one showed anatomical worsening. Hyperbaric oxygen therapy was considered a safe and tolerable treatment option for active CNV, potentially delaying its progression.

What This Means for Canadian Patients

This pilot study suggests that hyperbaric oxygen therapy could be a safe and tolerable option for Canadian patients with active choroidal neovascularization, potentially helping to delay disease progression. It might be used alone or in combination with existing anti-VEGF treatments to preserve vision.

Canadian Relevance

This study has no direct Canadian connection as it was conducted elsewhere and did not involve Canadian researchers or patients.

Study Limitations

The small sample size of seven patients and the lack of a control group limit the generalizability and definitive conclusions of this pilot study.

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Study Details

Study Type Pilot Study
Category Ocular / Retinal
Source Pubmed
PubMed ID 26094287
Year Published 2015
Journal Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc
MeSH Terms Aged; Aged, 80 and over; Analysis of Variance; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Choroidal Neovascularization; Combined Modality Therapy; Female; Humans; Hyperbaric Oxygenation; Intravitreal Injections; Macular Degeneration; Male; Middle Aged

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.