Hyperbaric oxygen therapy for radiation-induced tissue injury following sarcoma treatment: A retrospective analysis of a Dutch cohort | Canada Hyperbarics Skip to main content
Cohort Study PLoS One 2020

Hyperbaric oxygen therapy for radiation-induced tissue injury following sarcoma treatment: A retrospective analysis of a Dutch cohort

Generaal J, Lansdorp C, Boonstra O, van Leeuwen B, Vanhauten H, Stevenson M, et al. — PLoS One, 2020

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers retrospectively analyzed data from 30 sarcoma patients treated with hyperbaric oxygen therapy (HBOT) for radiation-induced complications in the Netherlands between 2006 and 2017.

What They Found

Of 16 patients treated for chronic wounds, 11 (68.8%) showed improved wound healing. Among 12 patients treated for late radiation tissue injury (LRTI), 9 (75.0%) reported reduced pain, and 5 of 8 (62.5%) experienced reduced fibrosis.

What This Means for Canadian Patients

Canadian sarcoma patients experiencing chronic wounds or late radiation tissue injury after treatment might consider discussing hyperbaric oxygen therapy with their healthcare providers. This therapy could potentially offer relief from pain and improve wound healing or reduce fibrosis.

Canadian Relevance

This study was conducted in the Netherlands and does not have a direct Canadian connection.

Study Limitations

This was a retrospective analysis with a small cohort of 30 patients, limiting the generalizability of the findings.

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Study Details

Study Type Cohort Study
Category Wound Care
Source Pubmed
PubMed ID 32511259
Year Published 2020
Journal PLoS One
MeSH Terms Adult; Aged; Aged, 80 and over; Chronic Disease; Cohort Studies; Combined Modality Therapy; Female; Humans; Hyperbaric Oxygenation; Male; Middle Aged; Netherlands; Radiation Injuries; Retrospective Studies; Sarcoma; Wound Healing; Young Adult

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.