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Clinical Study Journal of clinical gastroenterology 2001

Hyperbaric oxygen therapy for severe ulcerative colitis.

Buchman AL, Fife C, Torres C, Smith L, Aristizibal J — Journal of clinical gastroenterology, 2001

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers described the first successful use of hyperbaric oxygen therapy to treat severe ulcerative colitis that was refractory to conventional treatments.

What They Found

A patient with severe ulcerative colitis received 30 courses of 100% oxygen at 2.0 atm absolute. Clinical remission was achieved based on Truelove-Witts and disease activity index scores, and corticosteroids were successfully tapered off.

Canadian Relevance

This study has no direct Canadian connection as it was not conducted in Canada or by Canadian researchers.

Study Limitations

A major limitation of this study is its descriptive nature, likely representing a single case report, which limits generalizability.

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Study Details

Study Type Clinical Study
Category Wound Care
Source Pubmed
PubMed ID 11588553
Year Published 2001
Journal Journal of clinical gastroenterology
MeSH Terms Adult; Biopsy, Needle; Colitis, Ulcerative; Follow-Up Studies; Humans; Hyperbaric Oxygenation; Intestinal Mucosa; Male; Photomicrography; Sensitivity and Specificity; Severity of Illness Index; Treatment Outcome

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology