Hyperbaric Oxygen Therapy for Suburethral Vaginal Mucosal Necrosis after Interstitial Irradiation for Recurrent Cervical Cancer | Canada Hyperbarics Skip to main content
Case Report Case Rep Obstet Gynecol 2021

Hyperbaric Oxygen Therapy for Suburethral Vaginal Mucosal Necrosis after Interstitial Irradiation for Recurrent Cervical Cancer

Arakaki Y, Shimoji Y, Nakasone T, Taira Y, Nakamoto T, Kudaka W, et al. — Case Rep Obstet Gynecol, 2021

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers describe how hyperbaric oxygen therapy (HBOT) was used to treat a 76-year-old woman who developed severe tissue damage near her urethra after radiation therapy for cervical cancer.

What They Found

The patient received two cycles of HBOT, involving daily 60-minute sessions of 100% oxygen at 2.4 atmospheres absolute, five days a week for six weeks per cycle. Following treatment, the damaged tissue was completely replaced by normal mucosa, and no adverse effects were observed during the therapy.

Canadian Relevance

Although the study was conducted in Japan, it covers radiation-induced soft tissue necrosis, which is a Health Canada-recognised indication for hyperbaric oxygen therapy.

Study Limitations

As a single case report, the findings from this study cannot be broadly generalized to all patients with similar conditions.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Case Report
Category Radiation Injury
Source Pubmed
PubMed ID 34540299
Year Published 2021
Journal Case Rep Obstet Gynecol

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This study relates to Delayed Radiation Injury. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology