Hyperbaric oxygen therapy for treatment of a late presenting ischaemic complication from hyaluronic acid cosmetic filler injection. | Canada Hyperbarics Skip to main content
Case Study BMJ case reports 2022 Canadian

Hyperbaric oxygen therapy for treatment of a late presenting ischaemic complication from hyaluronic acid cosmetic filler injection.

Jalilian F, Hetz SP, Bostwick J, Boet S — BMJ case reports, 2022

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers presented a case of delayed ischaemic complication from a hyaluronic acid filler injection that was treated with hyaluronidase and hyperbaric oxygen therapy.

What They Found

A patient experienced ischaemic wound and mucosal necrosis within hours of a hyaluronic acid facial injection, but diagnosis and treatment were delayed for 5 days. Treatment included hyaluronidase followed by 14 daily sessions of hyperbaric oxygen therapy (HBOT). Despite the delay, the patient achieved essentially complete recovery.

Canadian Relevance

This case study was authored by Canadian researchers, indicating direct relevance to Canadian medical practice and patient care.

Study Limitations

As a single case report, the findings cannot be generalized to a broader patient population.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Case Study
Category Wound Care
Source Pubmed
PubMed ID 35798493
Year Published 2022
Journal BMJ case reports
MeSH Terms Cosmetic Techniques; Dermal Fillers; Humans; Hyaluronic Acid; Hyaluronoglucosaminidase; Hyperbaric Oxygenation; Injections, Subcutaneous; Ischemia

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology