Hyperbaric oxygen therapy in extremity trauma. | Canada Hyperbarics Skip to main content
RCT The Journal of the American Academy of Orthopaedic Surgeons 2004

Hyperbaric oxygen therapy in extremity trauma.

Greensmith JE — The Journal of the American Academy of Orthopaedic Surgeons, 2004

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reviewed the current evidence regarding the efficacy of hyperbaric oxygen therapy as an adjunctive treatment for extremity trauma.

What They Found

The review found that adjunctive hyperbaric oxygen therapy can enhance tissue oxygen content and may reduce the penumbra of cells at risk for delayed necrosis in crush injury or early compartment syndrome. Animal experiments, human case series, and recent randomised studies confirmed the efficacy of this therapy in patients with extremity trauma.

Canadian Relevance

This study has no direct Canadian connection as it was not conducted in Canada, nor does it involve Canadian researchers or patient populations.

Study Limitations

Further research is needed to establish additional indications, optimal timing, and appropriate dosing for hyperbaric oxygen therapy in extremity trauma.

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Study Details

Study Type RCT
Category Crush Injury
Source Pubmed
PubMed ID 15615503
Year Published 2004
Journal The Journal of the American Academy of Orthopaedic Surgeons
MeSH Terms Animals; Arm Injuries; Disease Models, Animal; Female; Humans; Hyperbaric Oxygenation; Injury Severity Score; Leg Injuries; Male; Multiple Trauma; Prognosis; Randomized Controlled Trials as Topic; Rats; Risk Assessment; Wound Healing

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology