Hyperbaric Oxygen Therapy in Immediate Tissue... (2025 study) Skip to main content
Study Ann Plast Surg 2025

Hyperbaric Oxygen Therapy in Immediate Tissue Expander-Based Breast Reconstruction

Zhu K, Heron M, Tiongco R, Biswas A, Weitzner A, Duclos O, et al., Ann Plast Surg, 2025

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers looked back at records of patients who had immediate breast reconstruction with tissue expanders to see how often hyperbaric oxygen therapy (HBOT) was used and what happened to patients who received it.

What They Found

This retrospective review covered 348 patients (552 breasts) who had tissue expander breast reconstruction, comparing prepectoral and subpectoral placement techniques. Only prepectoral patients received HBOT (19 patients, 33 breasts), and breasts treated with HBOT had higher rates of mastectomy skin necrosis than untreated breasts (73% vs 5.6% at 30 days, 76% vs 6.5% at 90 days), as well as higher rates of return to the operating room for necrosis removal and tissue expander removal. Among breasts that developed skin necrosis, those treated with HBOT had their mastectomy pocket salvaged more often than those without treatment (76% vs 41%, p less than 0.0001).

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

This is a retrospective, non-randomized study in which HBOT was given selectively to higher-risk prepectoral patients, making it impossible to separate the effect of HBOT itself from the underlying differences between patients who did and did not receive it.

This plain-language summary was generated with AI assistance from the study's abstract; it has not been individually reviewed by a clinician. Always consult the source study and a qualified healthcare professional. See our editorial policy.

Was this summary helpful?

Study Details

Study Type Study
Category Wound Care
Source Pubmed
PubMed ID 40167090
Year Published 2025
Journal Ann Plast Surg
MeSH Terms Humans; Female; Hyperbaric Oxygenation; Retrospective Studies; Tissue Expansion Devices; Middle Aged; Mammaplasty; Adult; Mastectomy; Surgical Flaps; Breast Neoplasms; Tissue Expansion; Treatment Outcome; Postoperative Complications; Aged

Cite This Study

Share

This study relates to Problem Wounds. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

Find a Canadian Clinic Treating Wound Care

Browse verified hyperbaric facilities across Canada.

View Canadian Facilities

Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last updated: March 19, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology