Hyperbaric Oxygen Therapy in Immediate Tissue Expander-Based Breast Reconstruction | Canada Hyperbarics Skip to main content
Study Ann Plast Surg 2025

Hyperbaric Oxygen Therapy in Immediate Tissue Expander-Based Breast Reconstruction

Zhu K, Heron M, Tiongco R, Biswas A, Weitzner A, Duclos O, et al. — Ann Plast Surg, 2025

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

US plastic surgeons reviewed 6 years of records from 348 women who had breast reconstruction with tissue expanders after mastectomy, comparing outcomes between those who received HBOT for skin complications and those who did not.

What They Found

All 19 patients who received HBOT had skin necrosis (tissue death) at the surgical site. Despite this, HBOT salvaged 76% of mastectomy pockets in treated patients, compared to only 41% in similar untreated patients (p < 0.0001), nearly twice the success rate. Complication rates stabilized between 30 and 90 days, suggesting HBOT's benefits are durable.

What This Means for Canadian Patients

Breast reconstruction after mastectomy is a common procedure for Canadian breast cancer survivors. When skin tissue starts dying after reconstruction surgery, HBOT can nearly double the chances of saving the reconstruction and avoiding a second major surgery.

Canadian Relevance

Compromised skin grafts and flaps are an OHIP-covered indication for HBOT in Ontario, making this finding directly applicable to reconstructive surgery patients in Ontario.

Study Limitations

This was a retrospective review at a single institution, and HBOT was only used in the most severe cases, making direct comparison with untreated patients inherently unequal.

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Study Details

Study Type Study
Category Wound Care
Source Pubmed
PubMed ID 40167090
Year Published 2025
Journal Ann Plast Surg
MeSH Terms Humans; Female; Hyperbaric Oxygenation; Retrospective Studies; Tissue Expansion Devices; Middle Aged; Mammaplasty; Adult; Mastectomy; Surgical Flaps; Breast Neoplasms; Tissue Expansion; Treatment Outcome; Postoperative Complications; Aged

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.