Hyperbaric oxygen therapy in inflammatory bowel disease: a systematic review and meta-analysis | Canada Hyperbarics
Meta-Analysis Eur J Gastroenterol Hepatol 2021

Hyperbaric oxygen therapy in inflammatory bowel disease: a systematic review and meta-analysis

Singh AK, Jha DK, Jena A, et al. — Eur J Gastroenterol Hepatol, 2021

Tier 1 — Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

Researchers conducted a systematic review and meta-analysis to evaluate the efficacy and safety of hyperbaric oxygen therapy (HBOT) for inflammatory bowel disease (IBD).

What They Found

The overall response rate for HBOT was 83.24% in ulcerative colitis and 81.89% in Crohn's disease. For fistulizing Crohn's disease, complete fistula healing was observed in 47.64% of patients, with partial healing in 34.29%. Most reported adverse events were minor.

What This Means for Canadian Patients

Hyperbaric oxygen therapy may offer a potential future treatment option for Canadian patients experiencing ulcerative colitis flares or Crohn's disease. However, patients should discuss current evidence with their gastroenterologist, as more definitive research is required before it becomes a standard therapy.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

The study's conclusions are limited by the reliance on observational studies and the need for adequately powered randomized controlled trials to draw definite conclusions.

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Study Details

Study Type Meta-Analysis
Category Wound Care
Source Pubmed
PubMed ID 33905214
Year Published 2021
Journal Eur J Gastroenterol Hepatol

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.