Hyperbaric oxygen therapy in the management of radiation-induced injury in the head and neck region: a review of the literature. | Canada Hyperbarics Skip to main content
RCT Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 2010

Hyperbaric oxygen therapy in the management of radiation-induced injury in the head and neck region: a review of the literature.

Spiegelberg L, Djasim UM, van Neck HW, Wolvius EB, van der Wal KG — Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2010

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers systematically reviewed experimental and clinical studies published between January 1990 and June 2009 on hyperbaric oxygen therapy for radiation-induced injury in the head and neck region.

What They Found

The review found that experimental research on hyperbaric oxygen therapy for radiation injury is scarce, and randomised controlled clinical studies are particularly lacking. Despite ongoing discussions, most reviewed studies suggest a beneficial role for hyperbaric oxygen therapy in previously irradiated tissue.

Canadian Relevance

This review has no direct Canadian connection as it did not involve Canadian researchers, institutions, or patient populations.

Study Limitations

A key limitation is the scarcity of robust experimental research and randomised controlled clinical studies on hyperbaric oxygen therapy for radiation-induced injury.

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Study Details

Study Type RCT
Category Radiation Injury
Source Pubmed
PubMed ID 20493616
Year Published 2010
Journal Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
MeSH Terms Animals; Cranial Irradiation; Head and Neck Neoplasms; Humans; Hyperbaric Oxygenation; Jaw Diseases; Osteoradionecrosis; Radiation Injuries; Xerostomia

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This study relates to Delayed Radiation Injury. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology