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Clinical Study Srpski arhiv za celokupno lekarstvo 2007

Hyperbaric oxygen therapy of angiopathic changes in patients with inherited gene imbalance.

Brkić P, Mitrović A, Rakić M, Grajić M, Jovanović T — Srpski arhiv za celokupno lekarstvo, 2007

View Original on PubMed PMID 18368909
Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers described a case study of monozygotic twins with type 2 diabetes and angiopathic changes, investigating the effects of hyperbaric oxygen therapy (HBO).

What They Found

One 54-year-old twin with a necrotic wound and 50 m claudication distance received 20 HBO treatments, which eliminated claudication and healed the wound. His monozygotic twin brother also presented with angiopathic changes due to diabetes, and both had chromosomal defects on pairs 3, 11, and 19.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

A significant limitation is that this study is a case report of only two individuals, limiting the generalizability of the findings.

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Study Details

Study Type Clinical Study
Category Wound Care
Source Pubmed
PubMed ID 18368909
Year Published 2007
Journal Srpski arhiv za celokupno lekarstvo
MeSH Terms Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Foot; Diseases in Twins; Humans; Hyperbaric Oxygenation; Male; Middle Aged; Mutation; Phenotype; Twins, Monozygotic

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This study relates to Problem Wounds. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology