Hyperbaric Oxygen to Assist Adults With Opioid Use Disorder in Reducing Methadone Dose | Canada Hyperbarics Skip to main content
RCT J Addict Nurs 2022

Hyperbaric Oxygen to Assist Adults With Opioid Use Disorder in Reducing Methadone Dose

Wilson M, Odom-Maryon T, Stanek K, Roush T, Muriungi J, Jesse A, et al. — J Addict Nurs, 2022

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

Researchers conducted a randomised controlled trial in the northwestern United States to investigate hyperbaric oxygen therapy (HBOT) as an adjunct to reduce withdrawal symptoms for adults initiating a medically supervised methadone dose reduction.

What They Found

Of the 17 participants randomised to HBOT, 13 (76.5%) underwent medical screening and sessions, with 9 (69.2%) completing all five 90-minute sessions. At 3 months, the HBOT group maintained an average 4.3-mg methadone dose reduction, compared with an average reduction of 0.25 mg for control group participants. Opioid withdrawal symptoms were also reduced by twice as much after Day 1 of HBOT compared with the control condition.

Canadian Relevance

This study was conducted in the United States and has no direct Canadian connection.

Study Limitations

The small sample size and single-site nature of this study limit the generalizability of its findings.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type RCT
Category Uncategorised
Source Pubmed
PubMed ID 35230058
Year Published 2022
Journal J Addict Nurs
MeSH Terms Adult; Humans; Hyperbaric Oxygenation; Methadone; Narcotics; Opioid-Related Disorders; Oxygen

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: March 19, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology