Hyperbaric oxygen treatment does not affect left ventricular chamber stiffness after myocardial infarction treated with thrombolysis. | Canada Hyperbarics Skip to main content
Clinical Study American heart journal 2004

Hyperbaric oxygen treatment does not affect left ventricular chamber stiffness after myocardial infarction treated with thrombolysis.

Vlahović A, Nesković AN, Dekleva M, Putniković B, Popović ZB, Otasević P, et al. — American heart journal, 2004

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers randomised 74 patients with acute myocardial infarction to receive either hyperbaric oxygen combined with streptokinase or streptokinase alone to assess its effect on left ventricular chamber stiffness.

What They Found

They found that hyperbaric oxygen treatment did not significantly affect left ventricular chamber stiffness, as measured by deceleration time, compared to streptokinase alone. For both groups, deceleration time decreased nonsignificantly from day 1 to day 3 and increased on day 7 (P <.001).

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

The study's findings are limited by its focus on a single echocardiographic parameter for stiffness and the relatively small sample size.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Clinical Study
Category Cardiac
Source Pubmed
PubMed ID 15215810
Year Published 2004
Journal American heart journal
MeSH Terms Aged; Combined Modality Therapy; Coronary Angiography; Echocardiography, Doppler; Female; Fibrinolytic Agents; Humans; Hyperbaric Oxygenation; Male; Middle Aged; Myocardial Infarction; Risk Factors; Streptokinase; Thrombolytic Therapy; Ventricular Dysfunction, Left

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology