Study BMJ Open 2023

Hyperbaric oxygen treatment in the management of necrotising soft-tissue infections: results from a Danish nationwide registry study

Hedetoft M, Madsen M, Hyldegaard O — BMJ Open, 2023

View Original on PubMed PMID 36813488

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a nationwide population-based registry study in Denmark to investigate the association between hyperbaric oxygen treatment and 30-day mortality in patients with necrotising soft-tissue infection.

What They Found

A total of 671 NSTI patients were included, with an overall 30-day mortality of 19% (95% CI 17% to 23%). Patients receiving HBO2 treatment (n=266) were younger and had lower SAPS II scores, but a larger fraction had septic shock compared to those not receiving HBO2.

Canadian Relevance

This study was conducted in Denmark and does not have a direct Canadian connection.

Study Limitations

As a registry study, it may be subject to limitations such as data completeness or unmeasured confounding variables.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type	Study
Category	Infection
Source	Pubmed
PubMed ID	36813488
Year Published	2023
Journal	BMJ Open
MeSH Terms	Humans; Male; Female; Shock, Septic; Hyperbaric Oxygenation; Oxygen; Prospective Studies; Soft Tissue Infections; Denmark

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: March 19, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology