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Clinical Study Anesteziologiia i reanimatologiia 1997

Hyperbaric oxygenation and antiaggregants: effects on platelet function in patients with ischemic heart disease.

Seriakov VV, Feofanova ID — Anesteziologiia i reanimatologiia, 1997

View Original on PubMed PMID 9221683
Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers studied platelet function in 65 chronic coronary patients receiving hyperbaric oxygenation and antiaggregant therapy.

What They Found

Hyperbaric oxygenation (8 to 12 sessions at 1.3-1.6 absolute atmosphere) had no proaggregant or antiaggregant effects on platelets. Aspirin in a daily dose of 125 mg and pentoxifylline in a daily dose of 300 mg reliably decreased the percentage of platelet aggregation and increased disaggregation. Hyperbaric oxygenation did not change the antiaggregant activity of these drugs.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

A limitation is that the study was conducted in 1997, and medical practices and antiaggregant therapies may have evolved since then.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Clinical Study
Category Cardiac
Source Pubmed
PubMed ID 9221683
Year Published 1997
Journal Anesteziologiia i reanimatologiia
MeSH Terms Aspirin; Blood Platelets; Coronary Disease; Female; Humans; Hyperbaric Oxygenation; Male; Middle Aged; Pentoxifylline; Phosphodiesterase Inhibitors; Platelet Aggregation; Platelet Aggregation Inhibitors; Time Factors

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology