Hyperbaric oxygenation combined with streptokinase for treatment of arterial thromboembolism of the lower leg. | Canada Hyperbarics Skip to main content
Clinical Study Wiener klinische Wochenschrift 2004

Hyperbaric oxygenation combined with streptokinase for treatment of arterial thromboembolism of the lower leg.

Mihaljević S, Mihaljević L, Majerić-Kogler V, Oremus K — Wiener klinische Wochenschrift, 2004

View Original on PubMed PMID 15038406
Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers presented a case report of a 74-year-old woman with acute lower leg arterial thromboembolism treated with combined hyperbaric oxygenation and streptokinase.

What They Found

After 60 minutes of hyperbaric oxygenation at 2.2 bar, the patient's severe ischaemic pain receded. Subsequent fibrinolytic therapy with streptokinase restored patency of the posterior tibial artery, verified by palpable pulsations and color Doppler ultrasonography. This combined approach resolved the ischaemia and prolonged tissue survival.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

A significant limitation of this study is that it is a single case report, limiting the generalizability of its findings.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Clinical Study
Category Cardiac
Source Pubmed
PubMed ID 15038406
Year Published 2004
Journal Wiener klinische Wochenschrift
MeSH Terms Aged; Combined Modality Therapy; Female; Fibrinolysis; Humans; Hyperbaric Oxygenation; Ischemia; Leg; Oxygen; Pain Measurement; Streptokinase; Thromboembolism; Tissue Survival; Treatment Outcome

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology