What Researchers Did
Researchers conducted a systematic review to compare the treatment of Fournier's gangrene with or without hyperbaric oxygenation as an adjunct therapy.
What They Found
Analyzing 13 studies involving 376 patients, researchers found a mortality rate of 16.6% in the hyperbaric oxygenation (HBO) group compared to 25.9% in the non-HBO group. Five retrospective case-control studies, encompassing 319 patients, contributed significantly to these findings.
Canadian Relevance
This systematic review did not include any studies specifically conducted in Canada or with a Canadian patient population.
Study Limitations
The systematic review noted a moderate to high risk of bias across the included studies, which could impact the certainty of the findings.