Iatrogenic ocular ischemic syndrome combined with central retinal artery occlusion following periorbital aesthetic Poly-D, L-lactic acid filler injections - a case report. | Canada Hyperbarics Skip to main content
Case Study Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology 2025

Iatrogenic ocular ischemic syndrome combined with central retinal artery occlusion following periorbital aesthetic Poly-D, L-lactic acid filler injections - a case report.

Chen IH, Cheng KC, Chen KJ — Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology, 2025

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers described a case of severe visual loss and eye pain in a patient who developed iatrogenic ocular ischemic syndrome and central retinal artery occlusion after receiving a Poly-D, L-lactic acid (PDLLA) filler injection in the nasal region.

What They Found

They found that a patient experienced severe visual loss and ophthalmalgia, diagnosed as iatrogenic ocular ischemic syndrome combined with central retinal artery occlusion, following a PDLLA filler injection. Despite various treatments including ocular massage, intravitreal Aflibercept, and Hyperbaric Oxygen Therapy, the patient's vision remained persistently impaired, marking this as the first reported case of this specific complication.

What This Means for Canadian Patients

Canadian patients considering Poly-D, L-lactic acid (PDLLA) filler injections, particularly in the nasal region, should be aware of the potential for rare but severe ophthalmic complications like vision loss. It is crucial to discuss all potential risks with their healthcare provider and ensure the practitioner has a thorough understanding of facial arterial anatomy.

Canadian Relevance

This study has no direct Canadian connection as it is a case report from outside Canada.

Study Limitations

As a single case report, the findings of this study cannot be generalized to a larger patient population.

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Study Details

Study Type Case Study
Category Ocular / Retinal
Source Pubmed
PubMed ID 40091289
Year Published 2025
Journal Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology
MeSH Terms Humans; Retinal Artery Occlusion; Dermal Fillers; Female; Cosmetic Techniques; Ischemia; Polyesters; Iatrogenic Disease; Middle Aged; Injections, Subcutaneous

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.