Impact of hyperbaric oxygenation therapy (HBOT) on renal function in human. | Canada Hyperbarics Skip to main content
Pilot Study Scientific reports 2025

Impact of hyperbaric oxygenation therapy (HBOT) on renal function in human.

Kanowski S, Shen Y, Klein T, Moeller MJ, Koch A, Theilig F — Scientific reports, 2025

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a pilot study with 23 healthy individuals to monitor changes in renal function parameters, including HIF-1α and erythropoietin, during 10 hyperbaric oxygenation therapy (HBOT) sessions.

What They Found

Among the 23 participants, heart rate decreased during HBOT sessions in both male and female individuals. Most renal function parameters, including serum HIF-1α and erythropoietin, blood pressure, and blood and urine values, remained unchanged, except for urine osmolality which showed a trend of alteration.

What This Means for Canadian Patients

Canadian patients undergoing hyperbaric oxygenation therapy (HBOT) for various conditions may find reassurance that the treatment generally does not appear to negatively impact key renal function parameters. This suggests that HBOT could be considered a relatively safe option for kidney health in otherwise healthy individuals.

Canadian Relevance

This pilot study has no direct Canadian connection.

Study Limitations

As a pilot study with a small sample size of 23 healthy individuals, these findings may not be generalizable to a broader patient population or those with pre-existing renal conditions.

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Study Details

Study Type Pilot Study
Category Cardiac
Source Pubmed
PubMed ID 40646131
Year Published 2025
Journal Scientific reports
MeSH Terms Humans; Hyperbaric Oxygenation; Male; Female; Kidney; Hypoxia-Inducible Factor 1, alpha Subunit; Adult; Erythropoietin; Pilot Projects; Middle Aged; Kidney Function Tests; Blood Pressure; Heart Rate

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.