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Clinical Study International wound journal 2019

Impaired wound healing secondary to bevacizumab.

Ahn JW, Shalabi D, Correa-Selm LM, Dasgeb B, Nikbakht N, Cha J — International wound journal, 2019

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

The researchers presented the histopathology findings of a non-healing ulcer in one patient receiving bevacizumab and observed the patient's response to hyperbaric oxygen therapy.

What They Found

They found specific histopathology findings in a non-healing ulcer in one patient treated with bevacizumab, suggesting insights into the drug's adverse reaction. Furthermore, this single patient showed a positive response to hyperbaric oxygen, indicating its potential as a treatment for bevacizumab-associated non-healing wounds.

What This Means for Canadian Patients

Canadian patients receiving bevacizumab who experience non-healing wounds might benefit from histopathological evaluation to understand the underlying cause. Hyperbaric oxygen therapy could be a potential treatment option for these challenging wounds, offering a practical approach to management.

Canadian Relevance

This study has no direct Canadian connection as it was not conducted in Canada or by Canadian researchers.

Study Limitations

The primary limitation of this study is that it is a single case report, meaning the findings may not be generalizable to a broader patient population.

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Study Details

Study Type Clinical Study
Category Wound Care
Source Pubmed
PubMed ID 31111622
Year Published 2019
Journal International wound journal
MeSH Terms Aged; Angiogenesis Inhibitors; Bevacizumab; Humans; Male; Pressure Ulcer; Treatment Outcome; Wound Healing

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.