Increased Radiosurgery Toxicity Associated With Treatment of Vestibular Schwannoma in Multiple Sclerosis. | Canada Hyperbarics Skip to main content
Review Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 2021

Increased Radiosurgery Toxicity Associated With Treatment of Vestibular Schwannoma in Multiple Sclerosis.

Wallerius K, Collins S, Forsthoefel M, Kim HJ — Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2021

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers presented a case report of a 52-year-old woman with multiple sclerosis who developed neurotoxicity after radiosurgery for a vestibular schwannoma and reviewed existing literature on this risk.

What They Found

The presented patient experienced grade 2 imbalance and new brain MRI hyperintensities 3 months after CyberKnife radiosurgery for a left-sided vestibular schwannoma. A literature review identified 19 other multiple sclerosis patients who developed radiation-induced toxicity following intracranial radiation therapy.

What This Means for Canadian Patients

Canadian patients with multiple sclerosis considering radiosurgery for vestibular schwannoma should be aware of a potentially increased risk of radiation-induced neurotoxicity. Clinicians should carefully weigh treatment options, discussing these risks thoroughly with patients to make informed decisions.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

The study's primary limitation is its reliance on a single case report and a literature review, which limits the generalizability of its findings.

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Study Details

Study Type Review
Category Radiation Injury
Source Pubmed
PubMed ID 33351559
Year Published 2021
Journal Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
MeSH Terms Cerebellum; Female; Humans; Magnetic Resonance Imaging; Middle Aged; Multiple Sclerosis; Neuroma, Acoustic; Radiosurgery; Retrospective Studies; Treatment Outcome

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.