Indications, therapeutic modalities and clinical outcomes of hyperbaric oxygen therapy in Italy, the ITA-OTI Study: a multicentre prospective observational study | Canada Hyperbarics Skip to main content
Prospective Study J Anesth Analg Crit Care 2026

Indications, therapeutic modalities and clinical outcomes of hyperbaric oxygen therapy in Italy, the ITA-OTI Study: a multicentre prospective observational study

Ippolito M, Martani L, Noto A, Maniscalco L, Spurio G, Nasello M, et al. — J Anesth Analg Crit Care, 2026

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a study across 10 centres in Italy to observe how hyperbaric oxygen therapy (HBOT) is currently used, including the reasons for treatment and how it is given.

What They Found

The study included 327 patients, with 73.7% receiving elective treatments and 26.3% urgent care. The most common reasons for HBOT were sudden hearing loss (35.8%), carbon monoxide poisoning (19.9%), and soft tissue infections (12.2%). Treatments typically involved 16 sessions at a median pressure of 2.5 ATA, with no serious adverse events reported.

What This Means for Canadian Patients

This study provides insights into HBOT use for conditions like carbon monoxide poisoning, which is a Health Canada-recognised indication. For Canadian patients with sudden hearing loss or certain soft tissue infections, these findings suggest how HBOT protocols might be structured and the types of outcomes to expect. The observed safety profile, with no serious adverse events, is also reassuring for patients considering HBOT.

Canadian Relevance

This study was conducted in Italy and does not involve Canadian authors or centres. However, it covers carbon monoxide poisoning, which is a Health Canada-recognised indication for hyperbaric oxygen therapy.

Study Limitations

As an observational study specific to Italy, this research describes current practices but does not compare HBOT to other treatments or evaluate long-term patient outcomes.

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Study Details

Study Type Prospective Study
Category Systematic Reviews
Source Pubmed
PubMed ID 42129901
Year Published 2026
Journal J Anesth Analg Crit Care

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.