What Researchers Did
Doctors described one patient with a severe crush injury to the right foot who developed a fungal infection and was treated with an antifungal drug combined with hyperbaric oxygen therapy.
What They Found
This is a single case report in which a foot infection caused by the fungus Absidia corymbifera resolved rapidly after treatment combining the antifungal drug ketoconazole with hyperbaric oxygen therapy (HBO). The report describes both clinical resolution (symptoms improved) and microbiological resolution (follow-up testing no longer detected the fungus). Because it is a report of a single patient, the abstract does not give numerical outcome data, session counts, pressure levels, or statistical comparisons beyond describing the resolution as rapid.
Canadian Relevance
No direct Canadian connection identified.
Study Limitations
This is a single case report with no control group, so it cannot separate the effects of the antifungal drug from those of hyperbaric oxygen therapy or confirm that the combination caused the resolution.