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Clinical Study Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc 2020

Influence of hyperbaric oxygen therapy on thrombus formation ability in humans.

Miike T, Sakamoto Y, Sakamoto Y, Matsuoka A, Shinada K, Nakayama K, et al. — Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc, 2020

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers analyzed changes in thrombus formation before and after hyperbaric oxygen therapy in six patients with skin and soft tissue ulcers or necrotic fasciitis.

What They Found

In six patients, the duration to pressure increase in blood samples after hyperbaric oxygen therapy was longer than before treatment (p<0.05). This indicated decreased clot adhesiveness and reduced clot formation ability, with T10 and T80 results further suggesting that HBO2 therapy reduced thrombus formation.

What This Means for Canadian Patients

For Canadian patients receiving hyperbaric oxygen therapy, these findings suggest a potential reduction in their ability to form blood clots. This could be a beneficial side effect, especially for those at risk of thrombotic events, though further research is needed to confirm clinical significance.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

A significant limitation of this study is its very small sample size of only six patients.

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Study Details

Study Type Clinical Study
Category Wound Care
Source Pubmed
PubMed ID 33227835
Year Published 2020
Journal Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc
MeSH Terms Aged; Blood Coagulation; Blood Platelets; Fasciitis, Necrotizing; Female; Humans; Hyperbaric Oxygenation; Male; Middle Aged; Skin Ulcer; Thrombosis; Ulcer

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.