International Multicenter Registry for Hyperbaric... (2022 study) Skip to main content
Study Undersea Hyperb Med 2022

International Multicenter Registry for Hyperbaric Oxygen Therapy: Results through June 2021

Harlan N, Ptak J, Rees J, Cowan D, Fellows A, Moses R, et al., Undersea Hyperb Med, 2022

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers built an international registry that collected data from patients treated with hyperbaric oxygen therapy at multiple centers and compared their health measures before and after treatment.

What They Found

This international registry study, which had no comparison group, gathered data from 2,880 patients across 22 centers, with delayed radiation injury, wound healing, and carbon monoxide poisoning among the most common reasons for treatment. Quality of life scores, head and neck radiation symptoms, wound healing scores (Strauss score), and hearing outcomes for idiopathic sudden sensorineural hearing loss were all reported as significantly improved after treatment, though the abstract does not give the specific score values. A further 125 patients were treated for indications not officially approved by the Undersea and Hyperbaric Medical Society. Complication rates were described as low and similar to those in earlier reports, though no specific rate is stated.

What This Means for Canadian Patients

For patients considering hyperbaric oxygen therapy for conditions such as carbon monoxide poisoning, radiation-related injury, non-healing wounds, or sudden hearing loss, this registry reports improvement measured before and after treatment. Because there was no comparison group, the study cannot show how much of that improvement came from the therapy itself versus other factors. The authors note that things like smoking and how severe the hearing loss was can affect outcomes, though this summary does not report specific results for those factors.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

The authors themselves note that the registry has no control group, so the improvements measured cannot be confidently attributed to hyperbaric oxygen therapy rather than other causes.

This plain-language summary was generated with AI assistance from the study's abstract; it has not been individually reviewed by a clinician. Always consult the source study and a qualified healthcare professional. See our editorial policy.

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Study Details

Study Type Study
Category Carbon Monoxide Poisoning
Source Pubmed
PubMed ID 36001560
Year Published 2022
Journal Undersea Hyperb Med
MeSH Terms Carbon Monoxide Poisoning; Hearing Loss, Sudden; Humans; Hyperbaric Oxygenation; Oxygen; Quality of Life; Registries

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This study relates to Carbon Monoxide Poisoning. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last updated: March 19, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology