Is it safe to use aluminum in the treatment of pediatric hemorrhagic cystitis? A case discussion of aluminum intoxication and review of the literature.

What Researchers Did

Researchers reported a case of aluminum toxicity in a 9-year-old girl treated for hemorrhagic cystitis and reviewed existing literature on aluminum toxicity in paediatric patients.

What They Found

They found that while intravesical aluminum treatment resolved hemorrhagic cystitis symptoms in a 9-year-old girl, she subsequently developed significant aluminum toxicity. The literature review highlighted that despite aluminum's documented efficacy in adults, its use in children has limited reports and carries a risk of devastating multisystem toxic effects.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

A limitation is that this study primarily presents a single case report and a literature review, which may not be generalizable to all paediatric patients.