What Researchers Did
Researchers investigated the effect of hyperbaric oxygenation (HBO) on keloid and non-keloid fibroblast growth and the expression of key growth factor messenger RNAs.
What They Found
They found that chronic exposure to hyperbaric oxygenation significantly decreased the growth of both keloid and non-keloid fibroblasts. This treatment also reduced the expression of messenger RNAs for insulin-like growth factor type 1 (ILGF-1) and transforming growth factor beta (TGF-β) in these cells.
What This Means for Canadian Patients
This research suggests that hyperbaric oxygenation could potentially be explored as a supplementary treatment to reduce keloid scar formation and growth. Patients suffering from problematic keloid scars might benefit from further investigation into HBO's therapeutic applications.
Canadian Relevance
This study has no direct Canadian connection.
Study Limitations
This in vitro study was conducted on isolated fibroblasts, meaning its findings may not directly translate to human patients.