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Review The Annals of otology, rhinology, and laryngology 2000

Laryngeal radionecrosis and hyperbaric oxygen therapy: report of 18 cases and review of the literature.

Filntisis GA, Moon RE, Kraft KL, Farmer JC, Scher RL, Piantadosi CA — The Annals of otology, rhinology, and laryngology, 2000

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reported on 18 patients with severe laryngeal radionecrosis treated with adjunctive hyperbaric oxygen therapy.

What They Found

Of 18 patients with severe laryngeal radionecrosis (2 grade 3, 16 grade 4), 13 (72.2%) experienced major improvement after a mean of 41 hyperbaric oxygen treatments. These 13 patients preserved their voice and deglutition and avoided total laryngectomy. The remaining 5 patients (27.8%) did not respond well to HBO and required total laryngectomy.

What This Means for Canadian Patients

Canadian patients suffering from severe laryngeal radionecrosis might consider hyperbaric oxygen therapy as a potential treatment to improve symptoms. This therapy could offer a chance to preserve their voice and avoid invasive procedures like total laryngectomy.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

This study is limited by its small sample size and observational case series design, lacking a control group for comparison.

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Study Details

Study Type Review
Category Radiation Injury
Source Pubmed
PubMed ID 10855566
Year Published 2000
Journal The Annals of otology, rhinology, and laryngology
MeSH Terms Adult; Aged; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Humans; Hyperbaric Oxygenation; Laryngectomy; Larynx; Male; Middle Aged; Necrosis; Otorhinolaryngologic Neoplasms; Prognosis; Radiation Injuries

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.