Case Study Stereotactic and functional neurosurgery 2012

Laser interstitial thermal therapy for focal cerebral radiation necrosis: a case report and literature review.

Rahmathulla G, Recinos PF, Valerio JE, Chao S, Barnett GH — Stereotactic and functional neurosurgery, 2012

View Original on PubMed PMID 22678505

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reported the first case of using laser interstitial thermal therapy (LITT) to treat medically refractory radiation necrosis in a 74-year-old patient and reviewed existing literature.

What They Found

The patient tolerated the LITT procedure well, being discharged 48 hours postoperatively. At 7-week follow-up, imaging showed near complete resolution of oedema and mass effect, and the patient was completely weaned off steroids.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

The primary limitation of this study is its nature as a single case report, which limits the generalizability of its findings.

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Study Details

Study Type	Case Study
Category	Radiation Injury
Source	Pubmed
PubMed ID	22678505
Year Published	2012
Journal	Stereotactic and functional neurosurgery
MeSH Terms	Aged; Brain; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Humans; Laser Therapy; Lung Neoplasms; Necrosis; Radiation Injuries; Radiotherapy; Treatment Outcome

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This study relates to Delayed Radiation Injury. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology