Retrospective Study Revista portuguesa de cirurgia cardio-toracica e vascular : orgao oficial da Sociedade Portuguesa de Cirurgia Cardio-Toracica e Vascular 2005

Long-term evaluation of chronic diabetic foot ulcers, non-healed after hyperbaric oxygen therapy.

Albuquerque E Sousa J — Revista portuguesa de cirurgia cardio-toracica e vascular : orgao oficial da Sociedade Portuguesa de Cirurgia Cardio-Toracica e Vascular, 2005

View Original on PubMed PMID 16474863

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a retrospective controlled study to evaluate the long-term effects of hyperbaric oxygen therapy (HBOT) on chronic diabetic foot ulcers that had not healed with standard treatment.

What They Found

Among 96 patients with chronic Wagner grades II-IV diabetic foot ulcers, 55 received HBOT while 41 did not. The HBOT group showed a significantly higher mean healing rate and significantly less need for amputation compared to the control group. The rate of minor amputation was also reduced by about two-thirds in the HBOT group.

Canadian Relevance

This study was not conducted in Canada and does not have a direct Canadian connection.

Study Limitations

As a retrospective study, it is subject to potential selection bias and confounding factors that may influence the observed outcomes.

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Study Details

Study Type	Retrospective Study
Category	Wound Care
Source	Pubmed
PubMed ID	16474863
Year Published	2005
Journal	Revista portuguesa de cirurgia cardio-toracica e vascular : orgao oficial da Sociedade Portuguesa de Cirurgia Cardio-Toracica e Vascular
MeSH Terms	Adult; Aged; Aged, 80 and over; Chronic Disease; Diabetic Foot; Female; Humans; Hyperbaric Oxygenation; Male; Middle Aged; Retrospective Studies; Time Factors; Treatment Failure

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Hyperbaric oxygen therapy facilitates healing of chronic foot ulcers in patients with diabetes

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Asian J Surg | 2022 Meta-Analysis

Efficacy of hyperbaric oxygen therapy for diabetic foot ulcers: an updated systematic review and meta-analysis

Zhang Z, Yang C, Jiang M, et al.

J Wound Ostomy Continence Nurs | 2017 RCT

Adjunctive hyperbaric oxygen therapy for healing of chronic diabetic foot ulcers: a randomized controlled trial

Chen CY, Wu RW, Hsu MC, et al.

This study relates to Problem Wounds. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology