Mild and Traditional Hyperbaric Oxygenation: Clinical Uses and Safety Considerations | Canada Hyperbarics Skip to main content
Review Undersea Hyperb Med 2026

Mild and Traditional Hyperbaric Oxygenation: Clinical Uses and Safety Considerations

Johnson-Arbor K — Undersea Hyperb Med, 2026

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a narrative review to compare the physiological effects, clinical uses, and safety of mild and traditional hyperbaric oxygen treatments.

What They Found

This narrative review found that traditional hyperbaric oxygen treatment promotes wound healing but is linked to adverse events, while mild hyperbaric oxygen treatment may benefit microcirculation and metabolism. Traditional HBOT causes systemic hyperoxia, which helps wound healing but can lead to oxygen free radical damage. Mild HBOT, using lower oxygen, might reduce oxidative damage and improve peripheral microcirculation, parasympathetic activity, and metabolism, though its use for wound treatment is not widely studied. Both types of HBOT carry serious risks, including chamber explosion and fire, which can be reduced by following safety standards.

What This Means for Canadian Patients

Canadian patients considering hyperbaric oxygen therapy should be aware of the differences between traditional and mild treatments, especially regarding their potential benefits for conditions like wound healing and their associated safety risks. Understanding these distinctions can help patients discuss the most appropriate and safest HBOT options with their healthcare providers.

Canadian Relevance

This study is not Canadian. However, its discussion of traditional HBOT's role in wound healing aligns with Health Canada-recognized indications such as diabetic foot ulcers.

Study Limitations

A limitation of this review is that mild hyperbaric oxygen treatment has not been extensively studied as a wound treatment, and compliance with safety standards for both types of HBOT can vary among facilities.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

Was this summary helpful?

Study Details

Study Type Review
Category Wound Care
Source Pubmed
PubMed ID 42365945
Year Published 2026
Journal Undersea Hyperb Med
MeSH Terms Hyperbaric Oxygenation; Humans; Oxygen; Wound Healing; Hyperoxia; Diving and Hyperbaric Medicine; Fires; Microcirculation; Oxidative Stress

Cite This Study

Share

This study relates to Problem Wounds. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

Find a Canadian Clinic Treating Wound Care

Browse verified hyperbaric facilities across Canada.

View Canadian Facilities

Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: July 3, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology