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Clinical Study The Journal of emergency medicine 2007

Mind the gap.

Akhtar J, Johnston BD, Krenzelok EP — The Journal of emergency medicine, 2007

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reported a case where recognizing an oxygen saturation gap, the difference between calculated blood gas and pulse oximeter readings, led to the diagnosis of carbon monoxide poisoning.

What They Found

They found that an "oxygen saturation gap" greater than 5% may indicate abnormal haemoglobin, such as from carbon monoxide poisoning, methemoglobinemia, or sulfhemoglobinemia. In the reported case, awareness of this gap, specifically exceeding 5%, was crucial for diagnosing carbon monoxide poisoning.

Canadian Relevance

This study has no direct Canadian connection as it was not conducted in Canada or by Canadian researchers.

Study Limitations

A significant limitation of this study is that it is a single case report, which inherently limits its generalizability to a broader patient population.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Clinical Study
Category Carbon Monoxide Poisoning
Source Pubmed
PubMed ID 17692762
Year Published 2007
Journal The Journal of emergency medicine
MeSH Terms Carbon Monoxide Poisoning; Humans; Hyperbaric Oxygenation; Male; Middle Aged; Oximetry; Oxygen; Suicide

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This study relates to Carbon Monoxide Poisoning. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology