Multiple osteolytic lesions of intraosseous adenoid cystic carcinoma in the mandible mimicking apical periodontitis | Canada Hyperbarics Skip to main content
Case Report Int Endod J 2012

Multiple osteolytic lesions of intraosseous adenoid cystic carcinoma in the mandible mimicking apical periodontitis

Grimm M, Henopp T, Hoefert S, Schaefer F, Kluba S, Krimmel M, et al. — Int Endod J, 2012

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers presented the case of a 55-year-old woman with intraosseous adenoid cystic carcinoma (ACC) in the mandible that later developed multiple distant metastases.

What They Found

Three years after initial treatment, the patient developed multiple lung metastases, followed by new metastatic lesions in the pancreas, mammary gland, and kidney five years post-resection. This case uniquely describes the manifestation of intraosseous ACC metastases in the breast and kidney, with the mammary gland metastasis staining positive for epithelial growth factor receptor.

What This Means for Canadian Patients

Canadian patients with adenoid cystic carcinoma should be aware of the potential for distant metastases, even years after initial treatment. This case highlights the importance of long-term follow-up and considering unusual sites for recurrence in ACC.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

As a case report, the findings are limited to a single patient and cannot be generalized to a broader population.

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Study Details

Study Type Case Report
Category Infection
Source Pubmed
PubMed ID 22712721
Year Published 2012
Journal Int Endod J
MeSH Terms Alveolar Bone Loss; Breast Neoplasms; Carcinoma, Adenoid Cystic; Cyclooxygenase 2; Diagnosis, Differential; Diagnostic Errors; Epidermal Growth Factor; Female; Humans; Hyperbaric Oxygenation; Kidney Neoplasms; Mandibular Neoplasms; Middle Aged; Osteomyelitis; Pancreatic Neoplasms; Periapical Periodontitis; Erb-b2 Receptor Tyrosine Kinases; Salivary Gland Neoplasms

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.