Normal physiologic carboxyhemoglobinemia of neonate masquerading as carbon monoxide poisoning | Canada Hyperbarics Skip to main content
Case Report Am J Emerg Med 2025

Normal physiologic carboxyhemoglobinemia of neonate masquerading as carbon monoxide poisoning

Hagemann J, Kozminski A, Miller S, Theiler C, McCabe D — Am J Emerg Med, 2025

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Emergency physicians documented a case where a newborn baby was transferred to a hospital with a falsely elevated carboxyhemoglobin (carbon monoxide) reading, triggering consideration of emergency HBOT, before doctors identified the true cause.

What They Found

The elevated carboxyhemoglobin level was caused by the natural breakdown of foetal haemoglobin in newborns by an enzyme called heme oxidase, not by carbon monoxide exposure. Once this was recognised, HBOT was appropriately withheld, avoiding unnecessary treatment and family stress.

Canadian Relevance

Carbon monoxide poisoning is an OHIP-covered indication for HBOT in Ontario. This case demonstrates that careful diagnosis is essential before proceeding with HBOT, particularly in neonates.

Study Limitations

This is a single case report and does not provide data on how frequently this diagnostic error occurs across hospitals or emergency departments.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Case Report
Category Carbon Monoxide Poisoning
Source Pubmed
PubMed ID 40555583
Year Published 2025
Journal Am J Emerg Med
MeSH Terms Humans; Carbon Monoxide Poisoning; Infant, Newborn; Carboxyhemoglobin; Diagnosis, Differential; Hyperbaric Oxygenation; Male; Female

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: March 19, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology