Case Report Diving Hyperb Med 2025

Novel use of hyperbaric oxygen treatment for treatment-resistant disseminated Saksenaea and Fusarium in a patient on extracorporeal membrane oxygenation (ECMO): a case report

Devaney B, Mathew J, Ferris S, Roberts L, Covelli C, Orosz J, et al. — Diving Hyperb Med, 2025

View Original on PubMed PMID 41364853

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers described successful HBOT treatment in a 20-year-old patient with life-threatening disseminated Saksenaea and Fusarium fungal infections following aviation trauma, while the patient remained on extracorporeal membrane oxygenation (ECMO).

What They Found

After 13 HBOT sessions at 2.4 ATA, local and systemic disease control was achieved within days of starting HBOT, despite prior failure of maximal surgical debridement and antifungal therapy. The patient survived and was discharged after prolonged rehabilitation.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

A single case report with concurrent multi-modal treatment cannot isolate HBOT contribution to the outcome.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type	Case Report
Category	Infection
Source	Pubmed
PubMed ID	41364853
Year Published	2025
Journal	Diving Hyperb Med
MeSH Terms	Humans; Male; Hyperbaric Oxygenation; Extracorporeal Membrane Oxygenation; Young Adult; Antifungal Agents; Fusariosis; Debridement; Amphotericin B; Immunocompromised Host; Fusarium; Mucormycosis

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: March 19, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology