What Researchers Did
Researchers treated two patients experiencing severe vision loss due to quinine toxicity with hyperbaric oxygen therapy to evaluate its effect on visual outcomes.
What They Found
Two patients who ingested 13-15 g of quinine presented with bilateral no light perception vision and dilated pupils. Following hyperbaric oxygen therapy, both patients achieved 20/20 visual acuity in both eyes within 24 hours of treatment. However, follow-up visual fields revealed bilateral constriction and paracentral scotomas.
Canadian Relevance
This study has no direct Canadian connection.
Study Limitations
A significant limitation of this study is its very small sample size of only two patients, which limits the generalizability of the findings.