What Researchers Did
Doctors reported the case of one woman whose eyes were severely damaged by Stevens-Johnson syndrome/toxic epidermal necrolysis, and treated her with major eye surgery followed by hyperbaric oxygen therapy (HBOT).
What They Found
This case report describes a single patient who received allogeneic limbal stem cell transplantation from her sister, along with salivary gland and oral mucosa tissue transplants, followed by daily HBOT to support the grafts and reduce inflammation. After 17 HBOT sessions combined with 3 months of autoserum eye drops, vision in her left eye improved from counting fingers to 0.4. The report does not separate how much of this improvement came from the surgery, the autoserum drops, or the HBOT itself.
Canadian Relevance
No direct Canadian connection identified.
Study Limitations
This is a single case report with no comparison group, so the vision improvement cannot be separated from the effects of the surgery and autoserum drops given at the same time, and the findings cannot be generalized to other patients.