What Researchers Did
Researchers conducted a prospective study to evaluate the natural course and effectiveness of conservative therapies for osteonecrosis of the femoral head, particularly in its early stages.
What They Found
Large and laterally located osteonecrosis lesions had an 80% probability of progressing to femoral head collapse within two years. Conservative therapies, including protected weight bearing, did not significantly alter the disease's natural course. Only rare, small to medium lesions in medial or central locations showed a good prognosis over five years.
What This Means for Canadian Patients
Canadian patients diagnosed with large or laterally located osteonecrosis of the femoral head should be aware of a high likelihood of progression to collapse within two years. Current conservative therapies may not significantly alter the disease's natural course, suggesting the need for more effective interventions.
Canadian Relevance
This study has no direct Canadian connection.
Study Limitations
The study notes a lack of MRI-controlled studies for early osteonecrosis and the absence of midterm results for newer therapeutic concepts.