Osteoradionecrosis of the cervical spine resulting from radiotherapy for primary head and neck malignancies: operative and nonoperative management. Case report. | Canada Hyperbarics Skip to main content
Case Study Journal of neurosurgery. Spine 2005

Osteoradionecrosis of the cervical spine resulting from radiotherapy for primary head and neck malignancies: operative and nonoperative management. Case report.

Donovan DJ, Huynh TV, Purdom EB, Johnson RE, Sniezek JC — Journal of neurosurgery. Spine, 2005

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reported three cases of cervical spine osteoradionecrosis following radiotherapy for primary head and neck malignancies, detailing their operative and nonoperative management.

What They Found

Two patients with severe spinal deformity and cord compression, who underwent surgical reconstruction with a vascularized fibular graft and instrumentation followed by hyperbaric oxygen (HBO) therapy, achieved fusion, restored spinal stability, and resolved neurological dysfunction at 2- and 4-year follow-ups. The third patient, who experienced pain and dysphagia without instability or neurological deficits, improved with HBO therapy alone.

Canadian Relevance

This case report does not have a direct Canadian connection.

Study Limitations

As a case report involving only three patients, the findings have limited generalizability to a broader patient population.

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Study Details

Study Type Case Study
Category Wound Care
Source Pubmed
PubMed ID 16370306
Year Published 2005
Journal Journal of neurosurgery. Spine
MeSH Terms Aged; Carcinoma, Squamous Cell; Cervical Vertebrae; Epidural Abscess; Head and Neck Neoplasms; Humans; Hyperbaric Oxygenation; Kyphosis; Magnetic Resonance Imaging; Male; Middle Aged; Osteomyelitis; Osteoradionecrosis; Radiation Injuries; Radiography

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology