Case Study American journal of otolaryngology 1999

Osteoradionecrosis of the cervical vertebrae and occipital bone: a case report and brief review of the literature.

Lim AA, Karakla DW, Watkins DV — American journal of otolaryngology, 1999

View Original on PubMed PMID 10609488

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers presented a case report of osteoradionecrosis affecting the cervical vertebrae and occipital bone in a patient treated for squamous cell carcinoma nine years prior.

What They Found

They identified the first reported case of osteoradionecrosis (ORN) involving the first and second cervical vertebrae and occipital bone. This occurred in a patient 9 years after treatment for squamous cell carcinoma, highlighting that ORN can develop in unusual locations with an insidious but rapidly progressive course.

Canadian Relevance

This study has no direct Canadian connection as it is a case report from the United States.

Study Limitations

As a single case report, the findings of this study cannot be generalized to a broader patient population.

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Study Details

Study Type	Case Study
Category	Wound Care
Source	Pubmed
PubMed ID	10609488
Year Published	1999
Journal	American journal of otolaryngology
MeSH Terms	Bone Diseases; Carcinoma, Squamous Cell; Cervical Vertebrae; Disease Progression; Fatal Outcome; Head and Neck Neoplasms; Humans; Male; Middle Aged; Occipital Bone; Osteoradionecrosis; Radiography

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology