Osteoradionecrosis of the jaw bones at the University of Kentucky Medical Center. | Canada Hyperbarics Skip to main content
Review The Journal of the Kentucky Medical Association 1989

Osteoradionecrosis of the jaw bones at the University of Kentucky Medical Center.

Patel P, Raybould T, Maruyama Y — The Journal of the Kentucky Medical Association, 1989

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reviewed the incidence of osteoradionecrosis (ORN) of the jaw in head and neck cancer patients treated with radiation therapy at the University of Kentucky Medical Center, comparing periods before and after an oral care program was instituted.

What They Found

Before 1974, osteoradionecrosis (ORN) of the jaw occurred in 10.9% of 220 irradiated cancer patients, but after an oral care program was implemented, the incidence declined to 2.7%. Specifically, from 1976 to 1985, only 3 out of 109 patients (2.7%) developed ORN of the mandible, and in 1986, only 1 of 30 patients experienced ORN.

What This Means for Canadian Patients

Canadian patients undergoing radiation therapy for head and neck cancer may benefit from comprehensive oral care programs to significantly reduce their risk of developing osteoradionecrosis. Implementing such programs could lead to fewer complications and improved quality of life following cancer treatment.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

This review is limited by its retrospective nature, reliance on data from a single institution, and its publication date in 1989, which may not reflect current treatment protocols.

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Study Details

Study Type Review
Category Radiation Injury
Source Pubmed
PubMed ID 2754311
Year Published 1989
Journal The Journal of the Kentucky Medical Association
MeSH Terms Head and Neck Neoplasms; Humans; Hyperbaric Oxygenation; Jaw Diseases; Osteoradionecrosis; Radiation Injuries; Radiotherapy

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.