What Researchers Did
Researchers tested how well a Baxter Patient-Controlled Analgesia (PCA) infusor device delivered medications under hyperbaric (increased pressure) conditions.
What They Found
They found that increased pressure, specifically at 2.3 atmospheres, caused an increase in the flow rate of the infusor devices. The flow increased by 4.27% for 5% dextrose, 1.79% for propofol, and 9.84% for 50% dextrose solutions. This suggests that the device's delivery rate changes when exposed to higher pressures.
Canadian Relevance
No direct Canadian connection identified. This study does not involve Canadian authors or a Canadian study site, nor does it focus on a specific Health Canada-recognized HBOT indication, but rather equipment used during the therapy.
Study Limitations
This study was conducted in 1994 and focused on a specific infusor model, which may not reflect the performance of newer or different drug delivery devices.