Preconditioning with hyperbaric oxygen in pancreaticoduodenectomy: a randomized double-blind pilot study. | Canada Hyperbarics Skip to main content
RCT Anticancer research 2014

Preconditioning with hyperbaric oxygen in pancreaticoduodenectomy: a randomized double-blind pilot study.

Bosco G, Casarotto A, Nasole E, Camporesi E, Salvia R, Giovinazzo F, et al. — Anticancer research, 2014

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a randomised double-blind pilot study with 21 patients undergoing pancreaticoduodenectomy to evaluate if a single preoperative hyperbaric oxygen treatment could reduce postoperative complications.

What They Found

Of the 21 patients, 10 (48%) received hyperbaric oxygen (HBO) and 11 (52%) received a placebo treatment the day before surgery. The pilot study results suggested that a single preoperative HBO treatment might reduce the overall complication rate following pancreatic resection.

Canadian Relevance

This study has no direct Canadian connection as it was conducted outside of Canada.

Study Limitations

A key limitation of this pilot study is its small sample size of 21 patients, which limits the generalizability and definitive conclusions.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type RCT
Category Infection
Source Pubmed
PubMed ID 24922652
Year Published 2014
Journal Anticancer research
MeSH Terms Adolescent; Adult; Aged; Aged, 80 and over; Combined Modality Therapy; Cytokines; Double-Blind Method; Female; Follow-Up Studies; Humans; Hyperbaric Oxygenation; Length of Stay; Male; Middle Aged; Oxygen Inhalation Therapy

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology